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A young woman, Miyako (Akane Miyako) responds to an advertisement for a live-in maid, and is given a job alongside the playfully alluring Mai-chan (Koshi Ann). Miyako quickly learns that housecleaning is the least of her duties, as the master (Maruyama Shogo) and his wife (Roman Soako) use the maids as toys in their unbridled erotic fantasies. Since Mai-chan possesses the uncanny ability to recover from any injury, no matter how severe, every violent desire is indulged, and Miyako soon finds herself actively involved in Mai-chan's horrific destruction (and miraculous resurrection). Based on the popular manga by Uziga Waita, Mai-chan's Daily Life is a diabolical dark comedy that takes fetish violence to shocking new extremes.
Convinced of the final outcome, a team of scientists travels back in time to stop the spread of a virus turning men into zombified rapists through society and causes them to finally uncover the source of the deadly disease which causes them to attempt to stop it before it happens again.