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When a car hits young Victor's pet dog Sparky, Victor decides to bring him back to life the only way he knows how. But when the bolt-necked "monster" wreaks havoc and terror in the hearts of Victor's neighbors, he has to convince them that Sparky's still the good, loyal friend he was.
Adrienne is trying to decide whether to stay in her unhappy marriage or not, and her life changes when Paul, a doctor who is travelling to reconcile with his estranged son, checks into an inn where she is staying.
Accomplished sailor Charlie St. Cloud has the adoration of his mother Claire and his little brother Sam, as well as a college scholarship that will lead him far from his sleepy Pacific Northwest hometown. But his bright future is cut short when tragedy strikes and takes his dreams with it. After high school classmate Tess returns home unexpectedly, Charlie grows torn between honoring a promise he made four years earlier and moving forward with newfound love. As he finds the courage to let go of the past for good, Charlie discovers the soul most worth saving is his own.
Robert Neville is a scientist who was unable to stop the spread of the terrible virus that was incurable and man-made. Immune, Neville is now the last human survivor in what is left of New York City and perhaps the world. For three years, Neville has faithfully sent out daily radio messages, desperate to find any other survivors who might be out there. But he is not alone.
After 39 years together, Ben and George finally tie the knot, but George loses his job as a result, and the newlyweds must sell their New York apartment and live apart, relying on friends and family to make ends meet.
After moving to a retirement community, loner Martha eventually befriends her fun-loving neighbor, Sheryl, and forms a cheerleading club for young-at-heart seniors, though they face roadblocks along the way.
Emilia, a law-school graduate, falls in love with her married boss, Jack. After Emilia marries Jack, her happiness turns unexpectedly to grief following the death of her infant daughter. Devastated, Emilia nonetheless carries on, attempting to forge a connection with her stepson William and to resist the interference of Jack's jealous ex-wife.
Maryann moves in with her grandparents after she's orphaned. Desperately lonely, she sets out to befriend a neighboring deathly ill, bed-ridden boy, despite the outright disapproval of his mother. Maryann's persistence pays off, however, and during a series of secret visits she gradually uncovers some seriously sinister goings-on in the house.
Teenagers Zach and Josh have been best friends their whole lives, but when a gruesome accident leads to a cover-up, the secret drives a wedge between them and propels them down a rabbit hole of escalating paranoia and violence.
A financial adviser drags his family from Chicago to the Missouri Ozarks, where he must launder $500 million in five years to appease a drug boss.