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Julius and Vincent Benedict are the results of an experiment that would allow for the perfect child. Julius was planned and grows to athletic proportions. Vincent is an accident and is somewhat smaller in stature. Vincent is placed in an orphanage while Julius is taken to a south seas island and raised by philosophers. Vincent becomes the ultimate low life and is about to be killed by loan sharks.
January 1978. After their success in England, the punk rock band Sex Pistols venture out on their tour of the southern United States. Temperamental bassist Sid Vicious is forced by his band mates to travel without his troubled girlfriend, Nancy Spungen, who will meet him in New York. When the band breaks up and Sid begins his solo career in a hostile city, the turbulent couple definitely falls into the depths of drug addiction.
Ex-football star Mike Gambril meets Terry McKay on a flight to Sydney, which is forced to land on a small atoll. They become romantic on board a ship sent to take them to a larger island. They agree to meet in New York three months later to see if the attraction is real. One shows up but the other doesn't. However, a chance meeting brings them together again.
Mary Ann Singleton, a naïve young secretary from the mid-west, tumbles head first into the colorful world of San Francisco, where carefree chaos revolves around the funky old apartment house at 28 Barbary Lane.