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A woman and her brother fly to New Guinea to look for a lost expedition, led by her husband, which has vanished in the great jungle.
Police detective Paolo Germi and the mysterious Marisa meet each other at a dance hall. Germi is unsuspecting of the secret Marisa is carrying with her: adverse conditions forced her into prostitution. As Germi finds the young girl brutally murdered, he decides to go after her killers. During his investigation, he enters a world of intrigue and obfuscation that leave an endless trail of blood.
Puglia, southern Italy, around 1400. A convent is invaded by the Tarantula cult, whose fanatical and crazed members desecrate the sacred place by committing obscene and bloody acts.