Space. The Final Frontier. The U.S.S. Enterprise embarks on a five year mission to explore the galaxy. The Enterprise is under the command of Captain James T. Kirk with First Officer Mr. Spock, from the planet Vulcan. With a determined crew, the Enterprise encounters Klingons, Romulans, time paradoxes, tribbles and genetic supermen led by Khan Noonian Singh. Their mission is to explore strange new worlds, to seek new life and new civilizations, and to boldly go where no man has gone before.

Cuban Bandleader Ricky Ricardo would be happy if his wife Lucy would just be a housewife. Instead she tries constantly to perform at the Tropicana where he works, and make life comically frantic in the apartment building they share with landlords Fred and Ethel Mertz, who also happen to be their best friends.

Mission: Impossible is an American television series that was created and initially produced by Bruce Geller. It chronicles the missions of a team of secret government agents known as the Impossible Missions Force. In the first season, the team is led by Dan Briggs, played by Steven Hill; Jim Phelps, played by Peter Graves, takes charge for the remaining seasons. A hallmark of the series shows Briggs or Phelps receiving his instructions on a recording that then self-destructs, followed by the theme music composed by Lalo Schifrin. The series aired on the CBS network from September 1966 to March 1973, then returned to television for two seasons on ABC, from 1988 to 1990, retaining only Graves in the cast. It later inspired a popular series of theatrical motion pictures starring Tom Cruise, beginning in 1996.

Special Agent Eliot Ness and his elite team of incorruptible agents battle organized crime in 1930s Chicago.

The Lucy Show is an American sitcom that aired on CBS from 1962–68. It was Lucille Ball's follow-up to I Love Lucy. A significant change in cast and premise for the 1965–66 season divides the program into two distinct eras; aside from Ball, only Gale Gordon, who joined the program for its second season, remained. For the first three seasons, Vivian Vance was the co-star. The earliest scripts were entitled The Lucille Ball Show, but when this title was declined, producers thought of calling the show This Is Lucy or The New Adventures of Lucy, before deciding on the title The Lucy Show. Ball won consecutive Emmy Awards as Outstanding Lead Actress in a Comedy Series for the series' final two seasons, 1966–67 and 1967–68.

The Life and Legend of Wyatt Earp is a television western series loosely based on the life of frontier marshal Wyatt Earp. The half-hour black-and-white program aired for 229 episodes on ABC from 1955 to 1961 and featured Hugh O'Brian in the title role.

Mannix is an American television detective series that ran from 1967 through 1975 on CBS. Created by Richard Levinson and William Link and developed by executive producer Bruce Geller, the title character, Joe Mannix, is a private investigator. He is played by Mike Connors. Mannix was the last series produced by Desilu Productions.

Johnny Slate successfully manages his circus as it moves from town to town.

December Bride is an American sitcom that aired on the CBS television network from 1954 to 1959, adapted from the original CBS radio network series that aired from June 1952 through September 1953.

Whirlybirds is a syndicated American drama/adventure television series, which aired for 111 episodes — broadcast from February 4, 1957, through January 18, 1960. It was produced by Desilu Studios . The show centered around Chuck Martin (Kenneth Tobey) and Pete (P.T.) Moore (Craig Hill), owners of 'Whirlybirds, Inc', who flew their helicopter (N975B) between Longwood Field and anywhere where they could be of help to someone in trouble.

The Texan was a Western television series starring popular B movie actor Rory Calhoun, which aired on the CBS television network from 1958 to 1960.

The Lucy–Desi Comedy Hour is a collection of thirteen one-hour specials airing occasionally from 1957 to 1960, and originally served as part of Westinghouse Desilu Playhouse. Its original network title was The Ford Lucille Ball-Desi Arnaz Show for the first season, and The Westinghouse Desilu Playhouse Presents The Lucille Ball-Desi Arnaz Show for the following seasons. It was the successor to the classic comedy, I Love Lucy, and featured the same major cast members. The production schedule avoided the grind of a regular weekly series. Desilu produced the show, which was mostly filmed at their Los Angeles studios with occasional on-location shoots at Lake Arrowhead, Las Vegas and Sun Valley, Idaho. CBS reran the show under the "Lucy-Desi" title during the summers of 1962-1967, after which it went into syndication.

The Ann Sothern Show is an American sitcom starring Ann Sothern that aired on CBS for 93 episodes. The series began on October 6, 1958, and ended on September 25, 1961. The Ann Sothern Show was Sothern's second sitcom for CBS. Her first series, Private Secretary, ended in 1957 after a contract dispute occurred between Sothern and Secretary's producer Jack Chertok. Several of Private Secretary's cast members appeared in the show.