After Homer accidentally pollutes the town's water supply, Springfield is encased in a gigantic dome by the EPA and the Simpsons are declared fugitives.

French nuclear tests irradiate an iguana into a giant monster that viciously attacks freighter ships in the Pacific Ocean. A team of experts, including Niko Tatopoulos, conclude that the oversized reptile is the culprit. Before long, the giant lizard is loose in Manhattan as the US military races to destroy the monster before it reproduces and it's spawn takes over the world.

Angelo "Snaps" Provolone made his dying father a promise on his deathbed: he would leave the world of crime and become an honest businessman. Despite having no experience in making money in a legal fashion, Snaps sets about to keep his promise.

"This Is Spinal Tap" shines a light on the self-contained universe of a metal band struggling to get back on the charts, including everything from its complicated history of ups and downs, gold albums, name changes and undersold concert dates, along with the full host of requisite groupies, promoters, hangers-on and historians, sessions, release events and those special behind-the-scenes moments that keep it all real.

Two high school girls wander off during a class trip to the White House and meet President Richard Nixon. They become the official dog walkers for Nixon's dog Checkers, and become his secret advisors during the Watergate scandal.

Set in Springfield, the average American town, the show focuses on the antics and everyday adventures of the Simpson family; Homer, Marge, Bart, Lisa and Maggie, as well as a virtual cast of thousands. Since the beginning, the series has been a pop culture icon, attracting hundreds of celebrities to guest star. The show has also made name for itself in its fearless satirical take on politics, media and American life in general.

Fernwood 2 Night was a comedic television program that ran from July 1977 – September 1977. It was created by Norman Lear and produced by Alan Thicke as a spin-off/summer replacement from Mary Hartman, Mary Hartman. It was a parody talk show, hosted by Barth Gimble and sidekick/announcer Jerry Hubbard, complete with a stage band, Happy Kyne and His Mirthmakers. Barth was the twin brother of Garth Gimble from Mary Hartman. Like Mary Hartman, Fernwood 2 Night was set in the fictional town of Fernwood, Ohio. The show satirized real talk shows as well as the sort of fare one might expect from locally-produced, small-town, midwestern American television programming. Well-known actors usually appeared playing characters or a contrivance had to be written for the celebrity to appear as themselves. After one season of Fernwood, the producers revamped the show the following year as America 2-Night. In this second version, Barth and Jerry's show moved to California and was broadcast nationally on the fictional UBS network, whose slogan was "We put U before the BS". This change allowed the show to now have well-known actors on the show as themselves.

Explore what makes us laugh, why, and how that's influenced our social and political landscape throughout history.