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Henelotter ups the ante in the final part of his trilogy by introducing a new member to the family: the potentially monstrous fruit of hideously deformed Belial's loins. With the pair still enjoying relative anonymity and comfort in their new found home (presided over by Granny Roth), things however take a downward turn on a trip to the Georgia Clinic of Uncle Hal, which leads to an encounter with an especially nasty redneck sheriff and his similarly blinkered band of merry men.
Having eluded the authorities after a series of grisly murders, the pair find sanctuary at the palatial home of Granny Ruth, an eccentric philanthropist who rallies the cause of "Unique Individuals". But even amongst "friends" the pair soon find themselves having to confront their murderous past.
A young man carrying a big basket that contains his deformed Siamese-twin brother seeks vengeance on the doctors who separated them against their will.