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Two miles into the earth, nine Appalachian miners struggle to survive after a methane explosion leaves them with one hour of oxygen.
After receiving an unsettling voicemail, Jordan (Wiggins) returns home, looking for answers, only to find her estranged father and even more questions. A demonic force has attached itself to the town and no one is safe. The only one who seems to know anything is the small town's Reverend.
After a comet releases a mysterious virus that begins to kill all of the women in the world, a young couple's relationship is severely tested. They hide out (from both the illness and the savages who hunt the remaining women) in their over-sterilized apartment. Ultimately the duo escapes their self-imposed quarantine to head to the wilderness.