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A "National Geographic" film crew is taken hostage by an insane hunter, who takes them along on his quest to capture the world's largest - and deadliest - snake.
The blood orchid - a rare flower that could hold the secret of eternal life and be worth a fortune to the company that finds it first. Led by a pharmaceutical research team, a scientific expedition sets out to go and explore deep into the jungles of Borneo to locate and bring back samples of the legendary plant. Battling through rainstorms to make their way upriver, the group encounters poisonous insects and a ferocious crocodile, only to discover they're being stalked by an even greater danger: a gathering of giant anacondas. Heat-sensing, fifty-foot-long flesh eaters that will go after anyone that crosses in their path.
This film tells the tale of the Harper Affair, in which young Jimmy Harper finds his life of promise turn into a life of debauchery and murder thanks to the new drug menace marijuana. Along the way he receives help from his girlfriend Mary and Jesus himself, but always finds himself in the arms of the Reefer Man and the rest of the denizens of the Reefer Den.