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Accused of killing his brother during adolescence, Salvador lives alone in the middle of Patagonia. Several decades later, his brother Marcos and his sister-in-law Laura, come to convince him to sell the lands they share by inheritance.
A mysterious epidemic spreads across the planet. Humanity develops an irrational fear of open spaces that causes instant death. Soon, the world population is trapped inside buildings. As Barcelona descends into chaos, Marc sets off on a quest to find Julia, his missing girlfriend, without ever going outside.