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The brutal hunt for the pure bloods continues as the ultimate vampire hunter, Blade, battles to defeat the House of Chthon, an ancient evil sect of vampires that is growing stronger everyday. Led by the vampire overlord Marcus, their objective is to create a vaccine that will give rise to a new breed of super vampires, immune to vampire weaknesses.
A missing FBI agent reappears six years after being declared dead.
Blade is a half-man, half-vampire who employs his extraordinary powers in a crusade to save mankind from the demonic creatures who walk the night. Set in Detroit, Blade investigates the vampire house of Chthon. Along the way he forms an uneasy alliance with Krista Starr, a former military veteran who becomes entrenched in the world of vampires while investigating the murder of her twin brother.
