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In post-war Italy, the family of typical housewife Delia is in turmoil over the impending engagement of beloved firstborn Marcella. The arrival of a mysterious letter, however, will ignite Delia's courage to face her abusive husband and imagine a better future.
Italian immigrant Francesca Cabrini arrives in 1889 New York City and is greeted by disease, crime, and impoverished children. Cabrini sets off on a daring mission to convince the hostile mayor to secure housing and healthcare for society's most vulnerable. With broken English and poor health, Cabrini uses her entrepreneurial mind to build an empire of hope unlike anything the world had ever seen.
Stella is a clumsy, cynical, imaginative and tormented teenage girl. After a life-changing car accident involving a dog, she convinces herself she must count her age in dog years: one year of her life counts for seven, and now that she’s turning sixteen, she is a centennial. For this reason, Stella thinks she has not much time left to live and pens a bucket list of all the things she would like to achieve before she dies.