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Having eluded the authorities after a series of grisly murders, the pair find sanctuary at the palatial home of Granny Ruth, an eccentric philanthropist who rallies the cause of "Unique Individuals". But even amongst "friends" the pair soon find themselves having to confront their murderous past.
Desperate to raise money for the experimental surgery that could restore his blind fiancee's eyesight, Toxie accepts a lucrative job with the evil multinational conglomerate Apocalypse Inc.