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Two alchemist brothers go on a quest for the Philosopher's Stone after an attempt to revive their dead mother goes horribly wrong.
In an alternate Japan, territorial street gangs form opposing factions collectively known as the Tokyo Tribes. The simmering tension between them is about to boil over into all-out war.
Born in 1937 in Osaka as the eldest daughter, Kawahara Kimiko moves to Shigaraki with her family at the age of 9. She works to support her family from a young age. Eventually, she jumps into the male world of pottery and becomes a pioneer of female ceramic arts. After marrying her husband who is also involved in ceramics and owning her own kiln, she raises her two children while struggling to create unique ware.
A brain surgeon named Minakata Jin has spent the last two years in anguish, as his fiancee lies in a vegetative state after an operation he performed. One day, he faints at the hospital and awakens to find himself transported back in time to the Edo period. He is soon attacked by a samurai, but he escapes with the help of a man named Kyotaro. Kyotaro suffers a serious injury to the head while trying to protect him, but Jin manages to save his life despite a lack of proper medical equipment. Because of that, Kyotaro's sister Saki begins taking an interest in Jin and becomes his assistant. Meanwhile, Jin is determined to find a way back to the present.
