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Dr. Gregory House, a drug-addicted, unconventional, misanthropic medical genius, leads a team of diagnosticians at the fictional Princeton–Plainsboro Teaching Hospital in New Jersey.
In this mismatched buddy cop dramedy, an amazingly handsome, happy-go-lucky FBI agent is paired with a local, hard scrabble Michigan homicide detective. As they solve crimes together, their polar opposite methods only slightly outweigh their disdain for each other.
Sir Arthur Conan Doyle, Harry Houdini and Stratton are tasked with the cases that nobody else can solve. It challenges their sense of what is real and what is not. Houdini is a skeptic, while Doyle believes in the unseen. Their diverse viewpoints make solving crime a challenge and often Stratton is put in the middle. The trio will take on cases that involve vampires, ghosts, monsters and poltergeists…or are they a ruse to conceal murder?