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When an in-flight collision incapacitates the pilots of an airplane bound for Los Angeles, stewardess Nancy Pryor is forced to take over the controls. From the ground, her boyfriend Alan Murdock, a retired test pilot, tries to talk her through piloting and landing the 747 aircraft. Worse yet, the anxious passengers — among which are a noisy nun and a cranky man — are aggravating the already tense atmosphere.
The U.S. has handed over control of its nuclear defense system to the Colossus supercomputer designed by scientist Dr. Charles Forbin. It soon becomes clear, that the now-sentient Colossus is far more intelligent than its creator realized—with the fate of the world hanging in the balance.
Sherlock Holmes is drawn into the case of Jack the Ripper who is killing prostitutes in London's East End. Assisted by Dr. Watson, and using information provided by a renowned psychic, Robert Lees, Holmes finds that the murders may have its roots in a Royal indiscretion and that a cover-up is being managed by politicians at the highest level, all of whom happen to be Masons.
Coogan, an Arizona deputy sheriff goes to New York to pick up a prisoner. While escorting the prisoner to the airport, he escapes and Coogan heads into the city to recapture him.