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Tourists take a boat to a remote island, where they find that most of the people have disappeared, and something is stalking them. They find a hidden room in the big mansion on a hill, and an ancient diary, which gives them clues to the source of the terror.
On the Caribbean island of Matul, white doctor David Menard is trying to stem the tide of cannibal zombies that are returning from the dead. Arriving on the island are Anne and reporter Peter West who are looking for Anne's missing father. The pair soon find themselves under attack from the zombies.