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It follows a group of vibrant teenagers in the early 1990s in Fucheng, a small coastal town in Southeast China. They passionately chase after their youth on the era's train, experiencing uninhibited growth and seeking an extraordinary transformation. In this radiant period of youth, they strive towards a brilliant era of personal growth and love.
Wei Wu Xian and Lan Wang Ji, two talented disciples of respected clans, meet during cultivation training and accidentally discover a secret carefully hidden for many years. Taking on the legacy of their ancestors, they decide to rid the world of the ominous threat.
Ruan Liu Zheng returns to her hometown after seven years, and becomes a neurosurgeon at Bei Ya Hospital. However, she did not expect to meet her ex-husband, Ning Zhi Qian, who is the most experienced neurosurgeon at Bei Ya Hospital. Ning Zhi Qian volunteers to be Ruan Liu Zheng's mentor, in order to make up for the hurt he caused her. Ruan Liu Zheng is no longer the weak and timid girl, and shows resolute and determination in both her work and relationship. During work, Ruan Liu Zheng clashes with Ning Zhi Qian, but also works alongside him to save lives. When they were in Africa to execute medical relief efforts, Ning Zhi Qian was injured while saving a patient. Ruan Liu Zheng did not leave his side, and fought hard to save him from the brink of death. Over time, the two gain a new understanding of life, and begin a new relationship.