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Zhou Ying is sold to the powerful Shen family by her foster father, yet successfully escapes by sneaking into merchant Wu Ping’s palanquin. The Wu family agreed to take her in after witnessing her remarkable business acumen, and she ends up marrying Wu Ping. The drama will chronicle the life of the Qing Dynasty's richest female merchant, and her struggles to keep the Wu family business afloat during the last years of the Qing Dynasty. Shen Xingyi is a happy-go-lucky young sir who has never known hardship in his life. After meeting Zhou Ying, he eventually decides to change his ways and becomes a mature noble who is willing to protect his country and family from disaster. He has a seemingly unrequited love for Zhou Ying.
Ren Xinzheng, a professor at the University of Traditional Chinese Medicine, is dedicated to spreading Chinese medicine. He resigned to set up a traditional Chinese medicine inheritance class, hoping to train successors who can truly pass on the way of Chinese medicine. Unscrupulous Sun Toutou also accidentally joined the mentoring class, and he was at odds with Ren Xinzheng's son Ren Tianzhen, Yang Xiaohong, who had changed his career as a lawyer, Peng Shiyan, a pediatrician at a tertiary hospital, and Zhao Liquan, who wanted to become a famous doctor with the expectation of the whole village, and other students were also incompatible.
