A series of romantic encounters between two heroines and four "virtual" idols. It's a call to return to reality, cherish life and reap a beautiful love. Lu Xiao is warm as spring in the virtual world but sensitive and lonely in real life. Jiang Kele may lead a difficult life, but she still dreams of meeting the perfect prince.

Towards the end of the Tang Dynasty, Zhu Wen usurped the throne and established the Liang Kingdom. A boy from the wild accidentally falls off a cliff while being pursued for saving wolf pups. He is rescued by Zhu Wen who adopts him as a son, and is renamed Zhu Youwen. Ten years later, the young boy has been conferred the title Prince of Bo and he meets and falls in love with Zhaixing, the daughter of a governor. Zhaixing discovers that Zhu Youwen is kind and righteous in spite of his status and the two become embroiled in a struggle for power.

The story is set a hundred years after a war between the Empire of Snow (Ice Tribe) and the Fire Tribe, where the Fire Tribe was defeated. However, the war was fatal, leaving Prince Ka Suo and his younger half-brother Ying Kong Shi the only royal heirs and pure-blood ice illusionists left in the Ice Tribe. Conflict ensues after Ka Suo reluctantly ascends to the throne as his lover, Li Luo, and his brother go missing. Ka Suo also accidentally discovers an evil presence lurking in the Ice Tribe's holy shrine. He and his companions enter the mysterious shrine, and defeat head of the shrine, Lady Yuan Ji, only to find out that she has been plotting a conspiracy against him. Ka Suo also experiences hardships in trying to find his lover and brother, not knowing that his brother has lost all of his memories and has become the Fire Prince under his mother's command. A war between the two tribes commences once again, with the two brothers pitted against each other.

In the late Southern Song Dynasty, as the Jin forces invaded, the Guo and Yang families faced tragedy. Taoist Qiu Chuji and the Seven Freaks of Jiangnan bet to train their descendants in martial arts. Guo Jing and Yang Kang, growing up under different circumstances, face various challenges. Guo Jing and Huang Rong develop a relationship amid turmoil, while Yang Kang's actions affect those around him.

Ren Xinzheng, a professor at the University of Traditional Chinese Medicine, is dedicated to spreading Chinese medicine. He resigned to set up a traditional Chinese medicine inheritance class, hoping to train successors who can truly pass on the way of Chinese medicine. Unscrupulous Sun Toutou also accidentally joined the mentoring class, and he was at odds with Ren Xinzheng's son Ren Tianzhen, Yang Xiaohong, who had changed his career as a lawyer, Peng Shiyan, a pediatrician at a tertiary hospital, and Zhao Liquan, who wanted to become a famous doctor with the expectation of the whole village, and other students were also incompatible.

Ruan Liuzheng returns to her hometown after seven years, and becomes a neurosurgeon at Beiya Hospital. However, she didn't expect to meet her ex-husband, Ning Zhiqian, who is the most experienced neurosurgeon. Ruan Liuzheng is no longer the weak and timid girl, and she shows resolute and determination in both her work and relationship. When they were in Africa to execute medical relief efforts, Ning Zhiqian was injured in a gunshot. Ruan Liuzheng didn't leave his side, and fought hard to save him from the brink of death. The two have gained a new understanding of life, and begun a new relationship again.

In 2008, Xiao Feng is a downcast e-sports team leader who is barely keeping his team together. E-sports is in its infancy and there is little money to be earned. Xiao Feng's team is looked down upon and ridiculed, yet they insist on fighting for their dreams. In 2019, Lu Xiao Bei is a genius in the same game, a masterful player. In reality, he is a disabled young man in a wheelchair. He vowed to continue his brother's legacy to become a professional e-sports player who died in an accident before he can turn pro. Despite living 11 years apart, a cosmic glitch allowed the two to communicate first by voice chat then meeting up in-game. This formed the basis of their friendship which transcend time and ultimately saved Xiao Feng's life in 2008. This allowed the two to meet face to face in the present. They then join forces and form their own team to achieve their ultimate goal of winning the championship.